Metabolism of Triphenylmethane and Triphenylcarbinol ’ H

;1 study of the metabolism of triphenylmethane and triphenylcarbinol in the rabbit indicates that the major urinary metabolite of these two compounds is the corresponding glucuronide. When 1 gm of triphenylmethane is fed to rabbits, approximately 357; of the dose is excreted unchanged in the feces, 45-55”,‘, is excreted in the urine as a glucuronide, and a small amount is converted to 4-hydroxytriphenymethane. Crinary excretion of triphenylcarbinol as the glucuronide accounts for approximately 430/; of a 1-gm dose fed to rabbits. Thirty-three c,‘O of the triphenylcarbinol is excreted unchanged in the feces.